Adrenaline or Epinephrine, the active principle of the medulla of the suprarenal gland, (cortical secretion not as yet isolated), is employed as a chemical messenger in the regulation of the activities of the body; in fact, its presence is essential to the activity of the sympathetic nerve. Adrenaline action on any part is the same as stimulation of the sympathetic nerve endings thereto. Local application (1: 1,000 solution) to mucous membranes promptly induces transient ischemia, seen in a blanching, persisting several hours from conjunctival instillation. Its action is very prompt, efficient, evanescent, owing to rapid oxidation and therefore practically harmless, unless too frequently repeated, when atheroma and heart lesions--myocardial--in animals have been reported. Arteries, heart, supra-renal bodies and vaso-motor system are prominently affected. The main action of Adrenaline is stimulation of the sympathetic endings, notably the splanchnic area, causing constriction of the peripheral arterioles, with resulting rise in blood pressure. This is especially observed in stomach, intestines; less in uterus, skin; nil in brain and lungs. Furthermore, is noticed, slowing of pulse, (medullary vagus stimulation), and strengthening of heart beat (increased myocardial contractility), resembling Digitalis; increased glandular activity, glycosuria; depression of respiratory center; contraction of muscular tissue of eye, uterus, vagina; relaxation of muscular tissue of stomach, intestines, bladder.
Natural
Key Symptoms & Indications
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Adrenaline or Epinephrine, the active principle of the medulla of the suprarenal gland, (cortical secretion not as yet isolated), is employed as a chemical messenger in the regulation of the activities of the body; in fact, its presence is essential to the activity of the sympathetic nerve. Adrenaline action on any part is the same as stimulation of the sympathetic nerve endings thereto. Local application (1: 1,000 solution) to mucous membranes promptly induces transient ischemia, seen in a blanching, persisting several hours from conjunctival instillation. Its action is very prompt, efficient, evanescent, owing to rapid oxidation and therefore practically harmless, unless too frequently repeated, when atheroma and heart lesions--myocardial--in animals have been reported. Arteries, heart, supra-renal bodies and vaso-motor system are prominently affected. The main action of Adrenaline is stimulation of the sympathetic endings, notably the splanchnic area, causing constriction of the peripheral arterioles, with resulting rise in blood pressure. This is especially observed in stomach, intestines; less in uterus, skin; nil in brain and lungs. Furthermore, is noticed, slowing of pulse, (medullary vagus stimulation), and strengthening of heart beat (increased myocardial contractility), resembling Digitalis; increased glandular activity, glycosuria; depression of respiratory center; contraction of muscular tissue of eye, uterus, vagina; relaxation of muscular tissue of stomach, intestines, bladder.
Physical Symptoms
Uses
Its chief therapeutic use depends on its vaso-constriction action; therefore a most powerful and prompt astringent and hæmostatic ; and invaluable in checking capillary hæmorrhages, from all parts, where local or direct application is feasible: nose, ear, mouth, throat, larynx, stomach, rectum, uterus, bladder. Hæmorrhagic condition not due to defective coagulation of the blood. Complete bloodlessness , ischemia, may be induced with impunity. Locally, solutions (1: 10,000-1: 1,000) sprayed or applied on cotton have been very efficient in bloodless operations about the eye, nose, throat, and larynx. Congestions of the ethmoid and sphenoid sinuses, also hay fever, have been markedly alleviated by warm spray of Adrenaline chloride, 1: 5,000. Here compare, Hepar 1x, which will start up secretions and so facilitate drainage. Werlhoff's disease, hypodermically, 1: 1,000. Externally, it has been used in neuritis, neuralgia, reflex pains, gout, rheumatism, as an ointment, 1-2 m of (1: 1,000) solution, along the nerve trunk at point of skin nearest its origin which could be reached (H. G. Carlton). Therapeutically, Adrenaline has been suggested in acute congestion of lungs, Asthma, Grave's and Addison's diseases, arterio-sclerosis, chronic aortitis, angina pectoris, hæmophilia chlorosis, hay fever, serum rashes, acute urticaria, etc. Dr. P. Jousset reports success in treating, homeopathically, cases of angina and of aortitis, sub-acute and chronic, when Adrenaline has been prescribed per os and in infinitesimal dose. The symptom guiding to this is, Sensation of thoracic constriction with anguish. This, with vertigo, nausea and vomiting have been produced by the drug. Abdominal pain. Shock or heart failure during anæsthesia, as it causes very prompt rise of blood pressure by its action on nerve endings in the vessel wall.
Mentions in Classic Materia Medicas
Explore detailed descriptions for this remedy across famous historical textbooks:
ADRENALINUM
Its chief therapeutic use depends on its vaso-constriction action; therefore a most powerful and prompt astringent and hæmostatic; and invaluable in checking capillary hæmorrhages, from all parts, where local or direct application is feasible: nose, ear, mouth, throat, larynx, stomach, rectum, uterus, bladder. Hæmorrhagic condition not due to defective coagulation of the blood. Complete bloodlessness, ischemia, may be induced with impunity. Locally, solutions (1: 10,000-1: 1,000) sprayed or applied on cotton have been very efficient in bloodless operations about the eye, nose, throat, and larynx.
Congestions of the ethmoid and sphenoid sinuses, also hay fever, have been markedly alleviated by warm spray of Adrenaline chloride, 1: 5,000. Here compare, Hepar 1x, which will start up secretions and so facilitate drainage. Werlhoff's disease, hypodermically, 1: 1,000. Externally, it has been used in neuritis, neuralgia, reflex pains, gout, rheumatism, as an ointment, 1-2 m of (1: 1,000) solution, along the nerve trunk at point of skin nearest its origin which could be reached (H. G. Carlton).
Therapeutically, Adrenaline has been suggested in acute congestion of lungs, Asthma, Grave's and Addison's diseases, arterio-sclerosis, chronic aortitis, angina pectoris, hæmophilia chlorosis, hay fever, serum rashes, acute urticaria, etc. Dr. P. Jousset reports success in treating, homeopathically, cases of angina and of aortitis, sub-acute and chronic, when Adrenaline has been prescribed per os and in infinitesimal dose. The symptom guiding to this is, Sensation of thoracic constriction with anguish. This, with vertigo, nausea and vomiting have been produced by the drug. Abdominal pain. Shock or heart failure during anæsthesia, as it causes very prompt rise of blood pressure by its action on nerve endings in the vessel wall.
Hypodermically, 1-5 m (1: 1,000 solution, as chloride) diluted in water. Internally, 5-30m of 1: 1,000 solution.
Caution.--On account of its affinity for oxygen, the drug easily decomposes in watery and dilute acid solutions. The solution must be protected from air and light. It must not be too frequently repeated, owing to cardiac and arterial lesions. For homeopathic use 2x to 6x attenuation.
Adrenalin.
Addison's disease. Adrenal neuralgia. Bronzed skin. Debility. Hæmaturia. Hyperæmia. Palpitation. Tachycardia.
Adrenalin has cured a number of cases of Addison's disease and has arrested others. The leading features of this affection may be taken as guides for its use: Bronzing of skin; loss of strength; wasting; exceedingly rapid pulse. It has cured a case of hæmaturia accompanied by pain in the adrenal region. It has been used locally in cases of hyperæmia of the conjunctiva, dissipating it almost immediately, and thus rendering operations possible. It appears to possess a very powerful local action over dilated blood-vessels. When injected into the circulation blood pressure rises, the arteries being contracted. The general muscular system is affected, a slight stimulus producing prolonged contraction.
ADRENALINUM
(Adrenal Glands)
PHARMACY - adren. Adrenalinum. Adrenal glands. Extract of adrenal glands. Sarcode. Tincture or Trituration. Historical dose: All potenc1e,.
CLINICAL- Addison's disease. Adrenalin neuralgias. Allergies. Angina pectoris. Asthma. Bronzed skin. Debility. Hematuria. Hemorrhages. Hyperemia. Neuralgia. Palpitations. Tachycardia.
HOMEOPATHIC- Adrenaline or Epinephrine, the active principle of the medulla of the suprarenal gland, is employed as a chemical messenger in the regulation of the activities of the body in fact, its presence is essential to the & activity of the sympathetic nerves.
Adrenaline appears to possess a very powerful local action over dilated blood vessel. When injected into the circulation, blood pressure rises, the arteries being contracted. The general muscular system is affected, a slight stimulus producing prolonged contraction.
Adrenalin has been suggested in acute congestion of lungs. Asthma. Addison's diseases and Grave's diseases, Arteriosclerosis, chronic aortitis, angina pectoris, hemophilia, chlorosis, hay fever, serum rashes. acute urticaria, etc.
Adrenalin's chief therapeutic use depends on its vasoconstriction action, therefore a most powerful and prompt astringent and hemostatic and invaluable in checking capillary hemorrhages from all parts, where local or direct application is feasible including the nose, ear, mouth, throat, larynx, stomach, rectum, uterus. and bladder.
Clinically effective in allergies, neuralgia, bronzed skin, debility, hematuria, palpitations, tachycardia, hyperemia, exceedingly rapid pulse, loss of strength, wasting. May well be needed in cancer patients with ad-renal disturbance. Prolonged contraction of the general muscular system. Great loss of strength, rapid emaciation. Rapid pulse and irregular intermitting heartbeats. General marked anemia.
MIND- Dependent and nervous. Ailme11tsfrom over work and stress. Apathy. Lack of interest in anything. No ambition. Disinclination for mental work. Absence of mental stamina and will power. Anxious and restless. Distracted easily. Aversion to mental activity. Cannot concentrate thoughts.
Abdomen - Rumbling in the intestines, borborygmus.
Back- Pain especially on the left side. better by sitting up straight or lying straight.
Ears - Aching in the left ear accompanies the headache, sharp pain in both ears at times. Itching and tickling in right ear, better by boring into ear with finger.
Eyes - Strained feeling as though he wanted to open them wide or press upon them. Pain in the right eye. Pressure on the eyes. Hyperemia of the conjunctiva. Aching in eyeballs, better by pressure and rubbing.
Face - Feels flushed but is not red. Flushes of heat over face and head, flushed throughout evening.
Food - Appetite increased. Ravenous hunger. Less thirst than usual. Thirst at times for large quantities. increased in the evening.
Head - Hot headache in left side, extending to right. Headache, worse by reading and in the morning, with a feeling as though the eyes were strained. Frontal headache with congested nose and eyes. Burning heat in head. Headache extending all overhead. Severe pain, better by pressure on the eyes. Headache with nausea and heat in face without redness. Neuralgic headaches. Brain feels swollen as though it were too large for skull. Flushes of heat in the evening over face and head.
Kidneys - Strong odor, hot and scalding, frequent, profuse, pale. Burning before and during urination. Sudden urgent desire to urinate. Amount of urine decreased; solids increased. Crystals of sodium oxalate increased while sodium urate appeared during the proving and was very prominent, no casts.
Limbs - Slight rheumatic pains coming and going down leg. Arms and legs go to sleep easily, numbness and tingling from below upwards. Cornsontheroes. Aching in limbs on waking in the morning, aching in the calves. Rheumatic pains in left elbow and little finger on waking. Legs tired and ache, especially in the calves and below the knees. Ankles feel weak and tired. Painful swelling on first finger of right hand, resulting in a felon. Tired aching in arms and legs on waking. Dull pain in arms and legs.
Lungs - Cough from irritation in supra-sternal fossa. Expectoration of gelatinous mucus. which is hard to detach. Increase of respiratory movements, soon followed by suffocation and death from paralysis of medulla and pneumogastric.
Male - Sexual desire increased without erections. Erections, lascivious dreams all night causing waking from sleep. Emissions in early morning without any bad effects.
Mouth - Bad taste on waking. Mouth filled with dark brown mucus, which has nasty taste. Tongue coated white, red edge and tip. Tongue clean anteriorly, mouth dry. Tongue coated white at times posteriorly.
Nose - Congested. full feeling in nose. Gelatinous mucus drops from the posterior sinuses, difficult to detach. On going out into the cold air had a copious, watery nasal discharge. Slight stuffiness in the nose with full feeling at the root of the nose.
Rectum - Passage of foul flatus. Stool loose, brown, semi-solid, passed quickly with fetid odor. Sudden spluttering diarrhea, all over in a minute, followed with burning in anus.
Sleep - Great sleepiness and drowsiness. Sleepy in evening and after a good night's sleep. Dullness and sleepiness from 3 p.m. to 6 p.m.
Stomach - Belching after meals. Sensation of nausea as though he would vomit. Pain in stomach passing from right to left, coming and going suddenly. Nausea before meals, though appetite is good after beginning to eat.
Throat - Much hawking to clear throat. Vocal cords inflamed, laryngeal catarrh, profuse secretion from the pharyngeal glands of whitish gelatinous mucus which was difficult to loosen. Right side swollen and sore, red and inflamed, worse by swallowing.
COMMENTS - Leading features include bronzing of the skin, loss of strength. Wasting and exceedingly rapid pulse. It has cured a case of hematuria accompanied by pain in the adrenal region.
Adrenaline has cured a number of cases of Addison's disease and has arrested others. It has been used locally in cases of hyperemia of the conjunctiva, dissipating it almost immediately and thus rende1ing operations possible.
Dr. P. Jousset reports success in treating, homeopathically, cases of angina and aortitis, sub-acute and chronic, when Adrenalin has been prescribed per as and in infinitesimal dose. The guiding symptom is a sensation of thoracic constriction with anguish. This, with vertigo, nausea and vomiting have been produced by the drug. Abdominal pain. Shock or heart failure during anesthesia.
Adrenaline causes very prompt rise of blood pressure by its action on nerve endings in the vessel wall.
REFERENCES - Allen. Boericke. Clarke. Grimmer. Phatak.
Remedy Profile
- Type Remedy
- Common Name N/A
- Origin Source Natural
Dosage & Potency
Hypodermically, 1-5 m (1: 1,000 solution, as chloride) diluted in water. Internally, 5-30m of 1: 1,000 solution. Caution.-- On account of its affinity for oxygen, the drug easily decomposes in watery and dilute acid solutions. The solution must be protected from air and light. It must not be too frequently repeated, owing to cardiac and arterial lesions. For homeopathic use 2x to 6x attenuation.
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